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phospho-EEF1A2(Ser358) Rabbit pAb (bs-14508R)  
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產(chǎn)品編號 bs-14508R
英文名稱 phospho-EEF1A2(Ser358) Rabbit pAb
中文名稱 磷酸化翻譯延伸因子EF-1 α2抗體
別    名 EEF1A2(phospho S358); p-EEF1A2(phospho S358); eEF1A 2; eEF1A-2; Eef1a2; EEF1AL; EF 1 alpha 2; EF-1-alpha-2; EF1A; EF1A2_HUMAN; Elongation factor 1 A 2; Elongation factor 1 alpha; Elongation factor 1 alpha 2; Elongation factor 1-alpha 2; Eukaryotic elongat  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 50 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human EEF1A2 around the phosphorylation site of Ser358: GY(p-S)PV 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

Subcellular Location:
Nucleus.

Tissue Specificity:
Brain, heart, and skeletal muscle.

Similarity:
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

SWISS:
Q05639

Gene ID:
1917

Database links:

Entrez Gene: 1917 Human

Entrez Gene: 13628 Mouse

Entrez Gene: 24799 Rat

Entrez Gene: 101109898 Sheep

Entrez Gene: 380550 Xenopus laevis

Omim: 602959 Human

SwissProt: Q05639 Human

SwissProt: P62631 Mouse

SwissProt: P62632 Rat

Unigene: 433839 Human

Unigene: 2645 Mouse

Unigene: 9764 Rat



產(chǎn)品圖片
Sample: HL-60 Cell (Human) Lysate at 40 ug Primary: Anti- phospho-EEF1A2(Ser358) (bs-14508R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 50 kD
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